Matthew G.
12/3/2025
While in town for a customer visit, I enjoyed dinner with a colleague. The service and food were outstanding. I'd recommend it.
Lewis and Clark's
$
Open
(291)
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217 S Main St
Saint Charles, MO 63301
Lewis & Clark's is an American-style restaurant located in St. Charles, Mo. It serves a variety of soups, salads, entrees, burgers, sandwiches and pasta. The restaurant also provides various Mexican dishes, beer and wines. Its entrees include pork chops, grilled chicken breasts, marinated tenderloins and shrimp. The restaurant s side dishes include baked potatoes, spinach dip, steamed vegetables and crispy fries. Its wine list features chardonnay, pinot grigio, zinfandel, merlot and cabernet. Additionally, the restaurant serves locally brewed beer from Trailhead Brewing Company. Lewis & Clark's also provides carryout services and a late night menu. Its carryout menu features onion rings, spinach quesadillas, fried shrimp, cheeseburgers, burritos and fried mushrooms.
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Reviews
3.5291 reviews
Nancy T.
1/4/2026
Service was good. Atmosphere is always good. Sat at a table upstairs for lunch to people watch and headed to the bar downstairs for more fun!
Cori M.
11/6/2025
First time here. Exceptional food! Tried the French Dip with Caesar salad and the half club with house salad. The food was delicious, the house dressing, a sweet vinaigrette, was extraordinary....
Micki E.
12/20/2025
When we visit St. Charles this is always a location that we can count on that will have good food options and good service. I like sitting upstairs because there is a nice view of the street.
Joshua D.
3/15/2025
Visited old St. Charles and took a walk to Lewis and Clark's (L&C) restaurant. Located on 3 floors L&C offers a great experience for lunch or dinner with reasonable prices. We stopped for lunch...
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