Pie-Sci

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5163 Trumbull St
Detroit, MI 48208

Pie-Sci is a Detroit-based pizzeria that offers a diverse range of pizzas, including vegetarian, dairy-free, vegan, and gluten-free options, all crafted with bold and inventive flavors. Their rotating, seasonal menu features both time-honored favorites and unique creations, and customers can choose to dine in, order for pickup, or enjoy their outdoor patio during the warmer months.

With a commitment to catering to various dietary preferences, Pie-Sci ensures that most pizzas can be made gluten-free, vegan, or lactose-free, offering Follow Your Heart mozzarella or house-made cashew cheese as vegan cheese options. Their meats are prepared in-house daily, guaranteeing fresh and savory flavors, while vegetarian protein substitutes like tofu bacon, vegan chicken, and jackfruit are available for those seeking plant-based alternatives. Whether it's their signature pizzas or their monthly salad specials, Pie-Sci aims to satisfy every pizza lover's cravings with their diverse and delicious offerings.

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Reviews

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4.5

(389)

Photo of LeAnne P.
LeAnne P.
9/5/2025

Calling all pizza snobs! Tired of traditional pizza toppings? Looking for an unforgettable pizza experience? This is the perfect place for you! Their creative, rotating menus guarantees something...

Photo of Hiiiii T.
Hiiiii T.
12/25/2025

this is one of those new trendy, hippy-dip restaurants that has randomly popped up in detroit, but has no clue where they actually are and what the culture entails. i came in here last week to...

Photo of Laz C.
Laz C.
7/28/2025

In town to catch a Tigers game and wanted pizza with both Vegan and Gluten Free options. Pie Sci to the rescue! They have your traditional choices along with Vegan and Gluten Free. It is a very...

Photo of Andrea D.
Andrea D.
12/28/2025

Yummy! I only like thin crust pizza, and this hit the spot. I had the BLT, which was delicious in the future. I'll get it with even more tomatoes. My daughter had the Keegan Michael gnocchi, two...

Photo of Demeka F.
Demeka F.
12/20/2025

This is one of the best gluten free dairy free pizzas I've ever had! I didn't know there was such a thing of GF thick crust, and when I finally found a spot with GF thick crust and DF cheese, I...

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